Whether caused by sunburn, bug bites, or an underlying skin condition like eczema, itchy skin is a common and often frustrating experience. According to board-certified dermatologist Dr. Teresa Song of Marmur Medical in New York City, itching is one of the most frequent complaints in dermatology, stemming from allergic reactions to dry skin. She notes that over-the-counter anti-itch creams can be incorporated into daily moisturizing routines to help improve baseline itching. However, if these options no longer control the itch, it is essential to seek professional medical advice to address potential underlying causes.
How Anti-Itch Creams Work
Dr. Song explains that a variety of mildly steroidal and steroid-free ingredients and formulations are available to improve the skin barrier, reduce inflammation, and instantly soothe irritation. However, the results of these anti-itch creams are temporary, and daily moisturizing aimed at repairing and strengthening the skin's barrier is most important. She recommends applying these creams immediately after showering while the skin is still damp to seal in moisture. If the creams are lightweight, consider adding a heavier moisturizer on top to enhance the effects.
Top Dermatologist-Recommended Anti-Itch Creams
1. Aquaphor Itch Relief Ointment
Hydrocortisone is a mild topical steroid that reduces inflammation and can be used for most causes of itching skin. Dr. Song recommends this 1% hydrocortisone ointment by Aquaphor because the hydrating and occlusive nature of the Aquaphor base makes it more effective. She cautions that steroids should be avoided for itching caused by superficial skin infections and healing wounds. Available in 2 oz ($16 at Amazon) and 1 oz ($13.49 at Target).
2. Cortizone 10 Maximum Strength Cream with Aloe
This maximum-strength hydrocortisone cream is supplemented with aloe, which Dr. Song describes as an anti-inflammatory and soothing ingredient that helps relieve irritated skin and associated itching. It is best for sensitive, post-sunburn, or postprocedural skin. This fast-working, fragrance-free cream claims to offer relief for up to 10 hours and can control inflammation from poison ivy, eczema, psoriasis, and more. Available at Amazon ($8), Target ($7), and Walmart ($8).
3. Dermeleve Anti-Itch Cream
Board-certified dermatologist Dr. Anar Mikailov recommends this dermatologist-developed steroid-free anti-itch cream. It contains aluminum acetate as an active ingredient for itchy skin, along with shea butter and ceramides. The cream also includes hyaluronic acid to draw moisture into the skin and strontium mineral salt, which has clinical evidence supporting its ability to suppress sensory irritation and histamine-induced itch. Dr. Mikailov advises against using antihistamine creams like Benadryl, as they can cause contact dermatitis. Available at Dermeleve ($25+).
4. TriCalm Anti-Itch Hydrogel
For those seeking a gel formula, Dr. Mikailov recommends TriCalm, which also uses aluminum acetate as an anti-itch ingredient. This soothing, steroid-free hydrogel is suitable for sensitive skin types and claims to offer rapid relief from itching, burning, and stinging associated with athlete's foot and bug bites. Available at Amazon and Walmart ($13).
5. Sarna Analgesic Daily Lotion
Both Dr. Song and Dr. Mikailov recommend Sarna's analgesic daily lotion. It contains pramoxine hydrochloride, which works by imparting a local numbing sensation to prevent sensing itch. The lotion also contains camphor and menthol for a cooling sensation. Dr. Song suggests the fast-absorbing sensitive formula. Available at Amazon ($15).
6. CeraVe Itch Relief Cream
This rich, custard-like cream features pramoxine hydrochloride as a targeted itch-relieving ingredient. It contains three essential ceramides, which Dr. Song explains are the skin's natural fatty acids that build the skin barrier. While it does not have active anti-itch properties, it strengthens the skin barrier to make it less reactive to common irritants, making it ideal for eczema patients. Available at Amazon ($22) and Walmart ($24).
7. Aveeno Eczema Therapy Nighttime Itch Relief Balm
Dr. Song recommends this steroid-free alternative that contains colloidal oatmeal for anti-inflammatory effects and ceramides for hydration. It acts as a skin-protective barrier that offers lasting moisture. Colloidal oatmeal is a trusted ingredient for eczema-related irritation, helping to rehydrate and calm irritated skin. Available at Amazon and Walmart ($20).
